Can you believe it is already Week 10 of the 2022 College Football season? Well, it is, and there are some huge matchups on Saturday that could go a long way in determining which teams end up making the College Football Playoff. The biggest game of the week, in case you have been living under a rock, is No. 1 Tennessee at No. 3 Georgia. The other huge matchup on Saturday will be No. 6 Alabama against No. 10 LSU. That being said, look out for No. 4 Clemson at Notre Dame as our guest writer thinks the Irish are going to give the Tigers quite the scare. Here are our College Football predictions for Week 10.

College Football Predictions: Which Top 25 teams will win in Week 10?
Here are all of the College Football predictions for this week's Top 25 games, via our guest picker, William Drysdale.
No. 2 Ohio State (59) over Northwestern (10)
No. 15 Penn State (38) over Indiana (10)
Michigan State (24) over No. 16 Illinois (21)
No. 4 Clemson (28) over Notre Dame (24)
No. 5 Michigan (52) over Rutgers (20)
No. 7 TCU (34) over Texas Tech (17)
No. 17 North Carolina (31) over Virginia (21)
No. 19 Tulane (45) over Tulsa (20)
No. 3 Georgia (45) over No. 1 Tennessee (20)
No. 8 Oregon (63) over Colorado (3)
No. 18 Oklahoma State (38) over Kansas (21)
Pittsburgh (34) over No. 20 Syracuse (33)
No. 25 UCF (48) over Memphis (42)
No. 10 LSU (38) over No. 6 Alabama (37)
No. 24 Texas (31) over No. 13 Kansas State (24)
No. 14 Utah (54) over Arizona (13)
No. 21 Wake Forest (42) over No. 22 North Carolina State (35)
No. 9 USC (40) over California (10)
No. 12 UCLA (17) over Arizona State (13)
What are your college football predictions for Week 10?