But the Patriots will also be looking to get back into the win column as they are coming off an overtime loss to the Green Bay Packers.
What is the opening point spread for Detroit Lions at New England Patriots?
This line has shifted in the direction of the Patriots as the game was listed at a pick'em on Wednesday.
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The Detroit Lions are in need of a win
With a win, the Lions would move to 2-3 on the season as they head into their bye week but if they were to fall to the Patriots, they will be 1-4 with an uphill battle in front of them.
Detroit Lions at New England Patriots: Who wins this Week 5 matchup?