6. 2010 – INDIANAPOLIS
- (5) Michigan State
- (2) West Virginia
- (5) Butler – Runner-up
- (1) Duke – Champion
Path to the Final Four
- First Round – W vs. (12) New Mexico State, 70-67
- Second Round – W vs. (4) Maryland, 85-83
- Sweet Sixteen – W vs. (9) Northern Iowa, 59-52
- Elite Eight – W vs. (6) Tennessee, 70-69
- Final Four – L vs. (5) Butler, 52-50
- The Spartans drew the 9-seed Northern Iowa Panthers in the Sweet Sixteen, who had knocked off the #1 overall seed in the tournament in the second round, the Kansas Jayhawks.
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